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Skin tags — medically called acrochordons — are small, soft growths that often appear in areas like the neck, armpits, groin, or under the breasts. While they’re completely benign, many people wonder: what actually causes them to grow?

At London Skin Clinic, we don’t just remove skin tags — we help our patients understand why they occur. Let’s explore the science and pathophysiology behind these common skin lesions.

🔍 What Are Skin Tags Made Of?

Skin tags are composed of:

  • An overgrown epidermis (outer skin layer)
  • A fibrovascular core — containing collagen, blood vessels, and occasionally fat

In simple terms, skin tags are tiny outpouchings of skin caused by a mix of friction, hormonal changes, and metabolic factors.

🔄 The Role of Friction

Most skin tags grow in areas where skin rubs against skin or clothing:

  • Neck
  • Armpits
  • Groin
  • Under the breasts
  • Eyelids

This constant mechanical friction can activate skin cells — particularly keratinocytes and fibroblasts — causing the skin to overgrow and form a tag.

🍩 Link with Metabolism: Insulin and Skin Growth

Studies show a strong connection between skin tags and insulin resistance, especially in people who are:

  • Overweight
  • Diabetic
  • Living with metabolic syndrome

Here’s how it works:

  • High insulin and IGF-1 (insulin-like growth factor) levels stimulate skin cells to grow
  • This leads to thickening of the outer skin and increased collagen in the dermis
  • Over time, this creates a soft, raised bump — a skin tag

🤰 Hormonal Triggers

Pregnancy is another common trigger. During this time, hormonal changes — particularly increased estrogen and progesterone — can:

  • Speed up epidermal cell turnover
  • Alter blood vessel formation in the skin

That’s why many pregnant women develop new skin tags, especially around the neck and underarms.

🧪 Do Viruses Play a Role?

Some researchers have found traces of HPV (human papillomavirus) DNA in skin tags — particularly types 6 and 11, which are also linked to warts. However:

  • Not all studies confirm this
  • Skin tags are not contagious or infectious like warts

So, HPV might play a minor role in some people, but it’s not considered a primary cause.

🧬 Are Skin Tags Genetic?

Yes — genetics likely play a role. If your parents had skin tags, you’re more likely to develop them. There’s also emerging evidence that certain growth factor genes and collagen-related enzymes may influence susceptibility.

🔬 What We See Under the Microscope

Histological studies show:

  • Thickened skin (acanthosis)
  • Loose collagen in the dermis
  • A central blood vessel core
  • No signs of malignancy (they’re benign)

🧑‍⚕️ Safe, Cosmetic Skin Tag Removal in London

At London Skin Clinic, our consultant plastic surgeons offer safe, scar-conscious skin tag removal using advanced surgical and cryotherapy techniques — often with same-day treatment. Whether your skin tags are causing irritation or simply bothering you cosmetically, we can help.

📍 Located on Harley Street

🚇 Easy access from Bond Street and Oxford Circus

🕒 Fast consultations and weekend availability

Want to Know More?

If you’re curious about skin tag removal or any other skin lesion, contact us today to book a consultation with a specialist.

📞 0203 916 6200

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